DMPQ- Explain the concept of mitochondrial gene therapy. Discuss how it can play important role in health sector.

. The recent success of gene therapy across multiple clinical trials has inspired a great deal of hope regarding the treatment of previously intractable genetic diseases. This optimism has been extended to the prospect of gene therapy for mitochondrial disorders, which are not only particularly severe but also difficult to treat. However, this hope must … Read more

DMPQ- Explain how Indigo cultivation became source of Indian farmer’s exploitation and how farmers resisted against it.

. By the thirteenth century Indian indigo was being used by cloth manufacturers in Italy, France and  Britain to dye cloth. By the end of the eighteenth century, the demand for Indian indigo grew further.  Britain began to industrialise, and its cotton production expanded dramatically, creating an enormous  new demand for cloth dyes. While the … Read more

DMPQ- What are yamanaka genes. Explain their role in our body.

Yamanaka factors (Oct3/4, Sox2, Klf4, c-Myc) are highly expressed in embryonic stem (ES) cells, and their over-expression can induce pluripotency in both mouse and human somatic cells, indicating that these factors regulate the developmental signaling network necessary for ES cell pluripotency. However, systemic analysis of the signaling pathways regulated by Yamanaka factors has not yet … Read more

DMPQ- . Write a short note on followings: (A) Performance budget (B) Revenue deficit (C) Quantitative Easing

(A) Performance budget Unlike the traditional line item budget, a performance budget reflects the  goal/objectives of the organization and spells out performance targets. These targets are sought to be achieved through a strategy(s). A Performance Budget gives an indication of how the funds spent are expected to give outputs and ultimately the outcomes. However, performance … Read more

DMPQ- Trace East India company’s response towards 1857 mutiny.

Company brought reinforcements from England, passed new laws so that the rebels could be convicted  with ease, and then moved into the storm centres of the revolt. Not only the police and military  personnel, but ordinary Britons were empowered to punish the Indians suspected of rebellion.  Rebellion had only one punishment – Death. Delhi was … Read more

DMPQ- Discuss the objectives and major features of PESA act of 1996.

The provisions of Part IX of the constitution relating to the Panchayats are not applicable to the Fifth Schedule areas. However, the Parliament may extend these provisions to such areas, subject to such exceptions and modifications as it may specify. Under this provision, the Parliament has enacted the “Provisions of the Panchayats (Extension to the … Read more